Two people were seriously injured in a head-on collision in Middleburg Wednesday morning.

The Florida Highway Patrol said the crash happened on Blanding Boulevard and State Road 16.

As of 10:40 a.m., all lanes going northbound and southbound at SR 21 and SR 16 are shut down, according to FHP.

Both individuals are reported to have serious injuries. They were transported to the Orange Park Medical Center.