The magnitude 7.8 temblor struck Wednesday night, one day after an 8.2 quake.
One day after a magnitude 8.2 quake rocked Chile, more temblors continue to rock the western coast of the country.
The largest, of magnitude 7.8, took place at 2:43 a.m. UTC or 10:43 p.m. ET, according to the U.S. Geological Service. That was one of several aftershocks that took place Wednesday night, including a 5.8-magnitude quake that took place at 11:14 p.m. ET.
The Tuesday quake killed four men and one woman and triggered a small tsunami. It took place about 60 miles northwest of Iquique.
Iquique saw seven-foot waves after the earlier quake, which has set off many aftershocks.
Iquique has been at the center of an area experiencing earthquakes in recent weeks.
On March 16th, a 6.7-magnitude temblor hit 37 miles from Iquique and a 6.1-magnitude quake took place in the same region a week later.