Indianapolis, IN (Sports Network) - Indianapolis had nothing to play for, but with Chuck Pagano back in charge, the inspired Colts may have shaken up the complexion of the AFC playoff picture.
Already locked into the fifth seed in the AFC, Andrew Luck threw two touchdown passes and the Colts remained unbeaten at home against the Houston Texans with a 28-16 triumph.
The 52-year-old Pagano, who was medically cleared by his doctor to return to his coaching duties last week, made his first sideline appearance since Week 3 following a successful battle with leukemia.
Under interim head coach Bruce Arians' watch, the Colts went 9-4 and secured a spot in the postseason after their win over the Kansas City Chiefs last Sunday.
Luck finished with 191 yards through the air on 14-of-28 efficiency for the Colts (11-5), who moved to 11-0 all-time against Houston in Indy.
Andre Johnson tallied 141 yards receiving on 12 catches for Houston (12-4), which dropped three of its last four games to close the season and could've locked up home-field advantage throughout the AFC playoffs with a victory.