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JACKSONVILLE, Fla. -- The NFL announced Thursday that Jacksonville Jaguars will host the San Francisco 49ers at its first London game at Wembley Stadium.

The Jaguars

committed to play one regular-season home game in the United Kingdom

in 2013, 2014, 2015, and 2016, all at Wembley Stadium.

The game is scheduled for Oct. 27, 2013 and is to kick off at 5 p.m. UK time (1 p.m. ET).

"By committing to play a regular-season home game in London in each of the next four years, the Jaguars will play a major role in helping grow our sport in the UK and beyond," said NFL Commissioner Roger Goodell. "We think Jaguars-49ers is a matchup our fans will really enjoy and a great way to start a new era in the international development of our game."

RELATED: Fans and business leaders weigh in on Jags' London games

Shad Khan, team owner of the Jaguars, confirmed the Jaguars' 2013 International Series opponent while speaking at the Leaders in Sport conference at Chelsea FC, the NFL announced.

"Everyone associated with the Jacksonville Jaguars is very much looking forward to our four home games in London through 2016, and we're particularly thrilled and honored that our first opponent will be the San Francisco 49ers," Khan said. "This is a unique and important opportunity for the Jaguars franchise, as well as for our fans and community. To share this stage in our first year at Wembley with a rising power like the 49ers will bring additional attention and respect to what we're trying to achieve as a franchise. We can't wait to see our global vision for the Jaguars become reality next season."

This will be the 49ers' second appearance in the International Series, the NFL elaborated. The 49ers hosted the Denver Broncos at Wembley Stadium in 2010, earning a 24-16 victory before a crowd of 83,941.

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