Colts owner James Irsay was arrested by Carmel Police Sunday night on preliminary drunken-driving charges and possession of a controlled substance, police said.
The bond for Irsay was set at $22,500, said Bryant Orem of the Hamilton County Sheriff's Department.
Carmel police say they will release details of the arrest soon.
In a tweet on Oct. 21, 2013, Irsay said he has not had a drink in 15 years.
In 2002, Irsay admitted he had an addiction to pain killers.
"After several years of orthopedic operations and procedures, accompanied by long bouts of chronic pain, I became dependent on prescription pain medications," Irsay said in a 2002 statement. "This summer I sought professional help at a nationally recognized facility located outside Indiana. I have successfully dealt with my dependence and my chronic pain issues."
Meg Irsay filed to divorce Jim Irsay last November. They had been married 33 years.
The Star obtained a copy of the three-page petition at the Hamilton County courthouse and it said, in part: "There has been an irretrievable breakdown of the marriage of the parties, and the Petitioner requests that the parties' marriage be dissolved."
The Colts were valued at $1.6 billion by Forbes magazine, 11th in the NFL.
The Colts said the divorce would not affect Jim Irsay's 100 percent ownership of the team.