An incident involving an American Airlines plane prompted a major emergency response at O'Hare International Airport, authorities said.

According to the Federal Aviation Administration, American Airlines Flight 383 was departing from O'Hare and was headed to Miami when it experienced "a problem during takeoff." American Airlines said the plane had an engine malfunction.

The pilots aborted the takeoff and passengers exited via a chute as flames were reported, authorities said.

Seven passengers and one crew member reported injuries and were transported to area hospitals for evaluation, the airline said in a statement. There were 161 passengers and nine crew members on the plane, the airline said.

Advocate Lutheran General Hospital said it was treating four people from the scene. Presence Resurrection Medical Center reported three patients from the scene in unknown condition.

The FAA reported that a runway was closed at the airport due to a "disabled aircraft." The FAA initially reported a ground stop at O'Hare after the incident, but the Chicago Department of Aviation said as of 3:30 p.m. three runways were closed at the airport. Ongoing delays were expected, airport officials said.

Chicago fire officials reported an emergency at the scene, saying "aircraft down at O'Hare."

The incident prompted an extra-alarm response.

The Chicago Department of Aviation said fire officials responded to an aircraft on fire.

Smoke and fire could be seen at the airport just after 2:30 p.m.

The National Transportation Safety Board said three investigators were being dispatched to Chicago following the fire.